17:30 uur 17-10-2023

Neu REFIX β-glucan vermindert spierfibrose in Duchenne spierdystrofie MDX-muizen, in gezamenlijk onderzoek met Dr. Yoshitsugu Aoki, NCNP, Tokio, Japan.

Publicatie in Scientific Reports toont ook aan dat ontstekingen onder controle zijn.

TOKIO–(BUSINESS WIRE)– De skeletspierfibrose die leidt tot motorische disfunctie bij Duchenne Muscular Dystrophy (DMD) kon aanzienlijk worden verminderd door louter orale consumptie van Neu-REFIX bèta 1,3-1,6 glucanen gedurende 45 dagen zonder andere geneesmiddelen, in MDX-muizenmodel van DMD. Dit onderzoek werd uitgevoerd in samenwerking met het team van Dr Yoshitsugu Aoki, hoofd afdeling moleculaire therapie, nationaal centrum voor neurologie en psychiatrie (NCNP), Tokio, Japan, een pionier in het ontwikkelen van oplossingen voor DMD zoals exon skipping therapie.

Dit persbericht bevat multimedia. Bekijk hier het volledige persbericht: https://www.businesswire.com/news/home/20231016668840/nl/

An illustrative summary of the research outcome with Neu REFIX Beta glucan presents, several “Firsts” to its credit; (1) Oral consumption of a food supplement alone, without any other drugs, reducing skeletal muscle fibrosis in MDX mice, (2) In clinical studies, increase in plasma dystrophin which is considered of relevance to correction of vascular smooth muscle pathology, (3) Clinically evident beneficial reconstitution of gut microbiome in patients with DMD in a 45- days clinical study, (4) Reduction of myocardial fibrosis with neu REFIX alone in MDX mice, (5) Slowing down the progress of DMD pathology evident by 6MWT, NSAA and MRC in a six-month clinical study when Neu REFIX was consumed along with standard of care medication; Neu REFIX 1,3-1,6 Beta glucan is a food supplement without any therapeutic claims; Not a drug or remedy to any illness. Research findings not to be construed as medical advice. Neu REFIX doesn’t contain any of the commonly notified 28 allergens.

An illustrative summary of the research outcome with Neu REFIX Beta glucan presents, several “Firsts” to its credit; (1) Oral consumption of a food supplement alone, without any other drugs, reducing skeletal muscle fibrosis in MDX mice, (2) In clinical studies, increase in plasma dystrophin which is considered of relevance to correction of vascular smooth muscle pathology, (3) Clinically evident beneficial reconstitution of gut microbiome in patients with DMD in a 45- days clinical study, (4) Reduction of myocardial fibrosis with neu REFIX alone in MDX mice, (5) Slowing down the progress of DMD pathology evident by 6MWT, NSAA and MRC in a six-month clinical study when Neu REFIX was consumed along with standard of care medication; Neu REFIX 1,3-1,6 Beta glucan is a food supplement without any therapeutic claims; Not a drug or remedy to any illness. Research findings not to be construed as medical advice. Neu REFIX doesn’t contain any of the commonly notified 28 allergens.

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